Xerclear® (Zoviduo®)

  • Mechanism

    Hydrocortisone and aciclovir combination

  • Disease areas

    Labial herpes

Xerclear® - Treatment of labial herpes (cold sores)

In 2009, Xerclear® (Zoviduo®) was approved for the treatment of labial herpes. The marketing rights to Xerclear® in the USA, Canada and Mexico were divested in 2010. The corresponding rights in Europe and the rest of the world have been outlicensed to Glaxo­SmithKline, with the exception of China, where Medivir has outlicensed the rights to Shijiazhuang Yuanmai Biotechnology Co Ltd. (SYB), and Israel and South America where Medivir has retained the rights.




Shijiazhuang Yuanmai Biotechnology Co Ltd.


Project Status and Medivir participation

Medivir receives royalties on sales of ­Xerclear®­/­(Zoviduo®) from GlaxoSmithKline. In addition, Medivir would receive milestones when Zoviduo® is approved as an over the counter product in certain new markets.

After market registration and production in China, Medivir will receive a fixed royalty from SYB for each unit sold and the agreement guarantees a minimum sale during the first three years on the market amounting to single-digit million amounts in SEK.

Projects from our team

Fostroxacitabine bralpamide (fostrox)

Nucleotide DNA polymerase inhibitor (oral)


HDAC inhibitor (topical)


Cathepsin K inhibitor (oral)